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Tassili N'Ajjer ... fungoid rock art ... enigmatic image thought to depict a human outlined with mushrooms ... so possibly shamanic in intention ... dated approximately 7000BC to 5000BC

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https://en.wikipedia.org/wiki/Tassili_Mushroom_Figure https://en.wikipedia.org/wiki/Tassili_n%27Ajjer https://whc.unesco.org/en/list/179/

Big Capital Muscles In to Psychedelics Medical Research and Development ... and Their Greed Will Fuck Things Up ...

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  https://japantoday.com/category/business/as-investors-pile-into-psychedelics-idealism-gives-way-to-pharma-economics

Do the therapeutic effects of psilocybin involve actions in the gut?

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A representative serotonin (5-HT) neuron and synapse. The figure shows predominant cellular locations of 5-HT receptors discussed in the text (5-HT 1 , 5-HT 2 and 5-HT 7 ), with their net effect on cellular activity denoted as excitatory (+) or inhibitory (−).  https://www.sciencedirect.com/science/article/abs/pii/S0165614723002766  Approximately 90% of the serotonin the  human body  produces is in the  gastrointestinal tract 's  enterochromaffin cells , where it regulates intestinal movements. https://en.wikipedia.org/wiki/Serotonin A Focus on Enterochromaffin Cells among the Enteroendocrine Cells: Localization, Morphology, and Role https://www.mdpi.com/1422-0067/23/7/3758 https://en.wikipedia.org/wiki/Enterochromaffin_cell

A team of researchers led by the University of Utah and the Natural History Museum of Utah (NHMU) has completed the largest genomic diversity study for the genus Psilocybe. Their genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced.

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  https://attheu.utah.edu/facultystaff/psychoactive-psilocybins-evolution-in-magic-mushrooms/

is the moral of this tale that anyone can become a shaman ? prob'ly not ...

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  https://flashbak.com/santa-on-shrooms-a-trippy-1943-comic-book-45038/

the jade canoe ... the spirit of haida qway ...

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  https://en.wikipedia.org/wiki/Spirit_of_Haida_Gwaii